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Advanced Glycation End Products Mediate Epigenetic Alteration of H3K27me3 in Renal Proximal Tubular Cells: Potential Role in Metabolic Memory.

Cells · 2025 · PMC12607550 · PMID 41227374

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Furthermore, a co-treatment with 5 μM DZNep and glycated-BSA further enhanced the expression of Ctgf and Snai1 relative to AGE-BSA alone, whereas the p27 Kip1 mRNA expression was higher than in AGE-BSA alone but did not reach statistical significance levels. 3.8.

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