Efficacy of Percutaneous Vertebroplasty Versus Placebo and Conservative Treatment in Osteoporotic Vertebral Fractures: An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Diagnostics (Basel) · 2025 · PMC12607622 · PMID 41225977

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

showed a trendp = 0.058so close (0.05 < p ≤ 0.1)

In the case of functionality, tests for differences between subgroups showed a trend toward significance in the short term ( p = 0.058) and statistically significant differences in the medium term ( p = 0.037), but non-significant in the long term ( p = 0.157).

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a trend toward significanceno p-value reported

In the medium term, PV showed benefits compared to placebo (SMD: −0.22; 95%CI: −0.40–0.04) but not compared to CT, although there was a trend toward significance (SMD: −1.00; 95%CI: −2.08 to 0.08).

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