Revisiting p53 Immunohistochemical Staining and Its Prognostic Implications in Advanced EGFR-Mutated Lung Adenocarcinoma.

Cancers (Basel) · 2025 · PMC12608574 · PMID 41228367

Europe PMC DOI

hedged sentence

0.0760

closest p · 1.5× alpha

0.0760

boldest claim

The sentences

showed a trendp = 0.076so close (0.05 < p ≤ 0.1)

Additionally, a trend toward better PFS was observed in patients with p53 positivity ≥50% (HR: 0.66 [95% CI: 0.40–1.08], p = 0.097), whereas patients harboring L858R showed a trend toward poor outcome (HR: 1.68 [95% CI: 0.95–2.97], p = 0.076).

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