SARIFA Is Associated with Lymph Node Metastases in PT3 and PT4 Gastric Cancers.

Cancers (Basel) · 2025 · PMC12609689 · PMID 41228384

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hedged sentences

0.0520

closest p · 1.0× alpha

0.1100

boldest claim

The sentences

a trend toward significancep = 0.052so close (0.05 < p ≤ 0.1)

In the multivariate model, the presence of SARIFA showed a trend toward significance in its association with lymph node involvement (OR = 4.886; 95% CI: 0.985–24.241; p = 0.052).

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did not reach statistical significancep = 0.11not close (p > 0.1)

FABP4, another gene reported to be associated with SARIFA, was expressed 1.56 times higher in SARIFA-positive gastric cancers, but this difference did not reach statistical significance ( p = 0.11, Wilcoxon test) ( Figure 5 ).

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marginally non-significantno p-value reported

Although this association was marginally non-significant in multivariate analysis, combining SARIFA with LVI in a composite variable improved predictive accuracy.

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