Platelet Releasate Reprograms Synovial Macrophages In Vitro: A New Approach in the Treatment of Hemophilic Synovitis.

Int J Mol Sci · 2025 · PMC12610548 · PMID 41226656

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did not reach statistical significanceno p-value reported

Even if the differential gene expression did not reach statistical significance, taking together the modulatory effect on surface markers and induction of TGF-β, these results further confirm that PRP treatment modulated the SF-induced profile.

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a decreasing trendno p-value reported

Furthermore, flow cytometry analysis in three follow-up patients showed a decreasing trend in CD11b + CD14 + CD64 + macrophages ( Figure 5 B).

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