The Impact on the Therapeutic Decision of Massive Gene Sequencing (NGS) in Plasma from Patients with Advanced Non-Small Cell Lung Cancer (NSCLC).

Cancers (Basel) · 2025 · PMC12611080 · PMID 41228262

Europe PMC DOI

hedged sentences

0.3400

closest p · 6.8× alpha

0.3400

boldest claim

The sentences

did not reach statistical significancep = 0.34not close (p > 0.1)

Patients receiving NGS-informed targeted therapy showed a numerically improved OS compared to those who did not, although this difference did not reach statistical significance ( p = 0.34).

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a favorable trendno p-value reported

Regarding prognostic impact, our data show a favorable trend in overall survival for patients who received targeted therapies guided by ctDNA results.

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