MitraClip procedure in patients with secondary mitral regurgitation: insights from Turkish experience.

BMC Cardiovasc Disord · 2025 · PMC12613571 · PMID 41225390

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.3100

boldest claim

The sentences

highly significantp < 0.001actually significant

All intermediate timepoints (3, 6, and 12 months) also showed highly significant improvements compared to baseline (all p < 0.001) with stable distributions compared to 1 month (all p > 0.05) (Fig. 2 ).

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approaching significancep = 0.09so close (0.05 < p ≤ 0.1)

BMI and diabetes mellitus, while approaching significance in univariate analysis ( p = 0.09 and p = 0.08), were excluded from final models due to loss of significance during stepwise selection (final p-values 0.24 and 0.18).

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did not achieve significancep = 0.31not close (p > 0.1)

Similarly, SGLT-2 inhibitor use showed a protective trend (HR 0.68) but did not achieve significance ( p = 0.31), likely due to low utilization (12.1%).

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failed to achieve significanceno p-value reported

With this small number, our ability to reliably identify independent predictors is limited, and variables appearing non-significant (such as LVEF, coronary artery disease) may actually be important predictors but failed to achieve significance due to insufficient power.

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