Additionally, an increase in the number of macrophages and natural killer (NK) cells, along with a clear trend toward a higher presence of cytotoxic CD8 T cells, was observed in CCA tumors from mice treated with ML792 (Supplemental Figure S8, http://links.lww.com/HEP/J724 ).
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Targeting protein hyper-SUMOylation halts cholangiocarcinoma progression by impairing cancer cell viability and tumor-stroma cross talk.
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