highly significantp < 1.0 × 10 -16
The network comprised 87 nodes and 1, 198 edges and showed highly significant enrichment (PPI enrichment p < 1.0 × 10 -16 ).
The network comprised 87 nodes and 1, 198 edges and showed highly significant enrichment (PPI enrichment p < 1.0 × 10 -16 ).
Consistent with these trajectories, FZD5, GTF2I , and hsa-miR-1976 were significantly upregulated in IHD, T2DM without complications, and T2DM+IHD versus healthy controls, whereas the overall reduction in LINC02210 across groups did not reach statistical significance ( P > 0.05), as summarized in Table 3 . 2.4.