Dietary β-Carotene, Vitamin A, and Retinol Intake and Prevalence of Colorectal Adenoma: A Cross-Sectional Study and Meta-Analysis.

Although β-carotene and vitamin A intake were associated with a decreasing trend in adenoma prevalence in both high-fat (>46 g/day) and low-fat (≤46 g/day) groups, the interactions were not statistically significant (p for interaction>0.05).

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In contrast, retinol intake showed a positive trend in adenoma prevalence in the high red meat group, although this did not reach statistical significance. 2.

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Meta-regression analysis indicated a marginally significant regional interaction (p for interaction=0.06) for β-carotene intake.

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We found that higher dietary β-carotene and vitamin A intake were associated with a lower prevalence of colorectal adenoma, while higher retinol intake showed an increasing trend.

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