nominally significantP value < 0.05
LDSC analysis reveals five red blood cell indices genetically correlated with sepsis Our global genetic correlation analysis using LDSC (summarized in Table 1 ) identified nominally significant (LDSC P value < 0.05) correlation between sepsis and multiple blood cell phenotypes, including mean corpuscular hemoglobin (MCH) (genetic correlation r g = 0.1286, P value = 0.0259), mean corpuscular volume (MCV) ( r g = 0.142, P value = 0.0094), mean reticulocyte volume (MRV) ( r g = 0.1181, P value = 0.0127), mean sphered corpuscular volume (MSCV) ( r g = 0.1242, P value = 0.0055), and red blood cell count (RBC) ( r g = −0.1084, P value = 0.0256).