Antithrombin-binding heparan sulfate is ubiquitously expressed in epithelial cells and suppresses pancreatic tumorigenesis.

Kaplan-Meier analysis also showed a trend between increased survival and higher HS AT staining, with a significant difference between patients exhibiting high staining or low staining (median survival 23.5 months [95% CI, 18.8–28.2] for low AT staining [average score <1] and 34.3 months [29.8–38.8] for high AT staining [average score ≥1]; log-rank test P = 0.002) ( Figure 5, D and E ).

also in 53,322 other papers