Fc-Modified IVIG with Enhanced Blood-Brain Barrier Penetration Ameliorates Cognitive Deficits and Neuropathology in A53T α-Synuclein Transgenic Mice.

Cell Mol Neurobiol · 2025 · PMC12618800 · PMID 41236640

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0.0820

closest p · 1.6× alpha

0.0820

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The sentences

did not reach statistical significanceP = 0.082so close (0.05 < p ≤ 0.1)

In the hindlimb clasping test, IVIGA treatment showed a tendency to reduce clasping severity in A53T α-syn transgenic mice, but the difference did not reach statistical significance (Kruskal–Wallis followed by Mann–Whitney U test, P = 0.082) (Fig. 2 B, C ).

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