Immune tolerance induction using the thyrotropin receptor epitope 78-94 (p37) prevents Graves' disease in HLA-DR3 transgenic mice.

Front Immunol · 2025 · PMC12620236 · PMID 41256857

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did not reach statistical significanceno p-value reported

Although the differences did not reach statistical significance, the step-up protocol with p37 up to 50 μg consistently demonstrated superior control of serum FT4 levels and TRAb suppression ( Figures 4A, B ).

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