Factors Associated With Initiation of Sodium-Glucose Cotransporter 2 Inhibitor and Glucagon-Like Peptide 1 Receptor Agonists in Patients With Diabetes and Kidney Disease: A Post Hoc Analysis of the Kidney CHAMP Trial.

Diabetes Spectr · 2025 · PMC12620743 · PMID 41257235

Europe PMC DOI

hedged sentences

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closest p · 1.0× alpha

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boldest claim

The sentences

a trend toward significanceP = 0.05actually significant

However, in the fully adjusted analysis, only A1C remained significant (IRR 1.04, 95% CI 1.01–1.08, P = 0.015), and BMI showed a trend toward significance (IRR 1.04, 95% CI 1.00–1.08, P = 0.05).

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did not reach statistical significanceno p-value reported

Similarly, we saw a trend toward increased target medication use with CKD stage 3b or worse in the intervention arm, but this trend did not reach statistical significance.

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