a significant trendp=0.02
Using data on employment history, females showed a higher risk of moderate–severe asthma associated both with higher monthly number of night shifts (OR 1.39 (95% CI 1.04–1.88) for >10 night shifts per month; model 2, supplementary table 6 ) and with higher lifetime duration of night shifts (OR 1.28 (95% CI 1.03–1.59) for >10 years of night shifts; model 2, supplementary table 7 ), but a significant trend was found only among females for lifetime duration (p=0.02).