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ST6GAL1-Mediated Sialylation Stabilizes PD-L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer.

Adv Sci (Weinh) · 2025 · PMC12622430 · PMID 40847469

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did not reach statistical significancep = 0.056so close (0.05 < p ≤ 0.1)
a positive trendno p-value reported
Although the difference in PD‐L1 expression between the ST6GAL1‐positive and ‐negative groups did not reach statistical significance (p = 0.056), a positive trend was observed, suggesting a potential correlation between ST6GAL1 and PD‐L1 (Figure 4A,B ).

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