Beckwith-Wiedemann syndrome and large offspring syndrome involve alterations in methylome, transcriptome, and chromatin configuration.

NAR Mol Med · 2025 · PMC12622693 · PMID 41256768

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However, IGF2R showed a trend of downregulation (1.7X, FDR = 0.058) in BWS subgroup 1 which is similar to LOS, and could be associated with the MAS1 misregulation ( Supplementary Fig.

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