Nonlinear Association Between the C-Reactive Protein-Triglyceride-Glucose Index and Rheumatoid Arthritis Risk: The Mediating Role of Body Mass Index.

In the unadjusted model (Model 1), RA risk increased sharply once CTI exceeded approximately 7.0, with a highly significant overall association ( p < 0.001) and clear evidence of nonlinearity ( p -nonlinear <0.001).

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Although the association did not reach statistical significance among Mexican Americans and other minority groups—likely due to smaller subgroup sizes—no interaction by race/ethnicity was detected ( p = 0.353).

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