Adjuvant chemoradiotherapy with procarbazine, lomustine, and vincristine (PCV) or temozolomide for 1p/19q Co-deleted anaplastic oligodendroglioma: a systematic review and network meta-analysis.

BMC Cancer · 2025 · PMC12625344 · PMID 41254593

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0.4210

closest p · 8.4× alpha

0.4210

boldest claim

The sentences

showed a trendp = 0.421not close (p > 0.1)

The network meta-analysis, compared with RT alone, RT + PCV significantly improved OS (HR: 0.617; 95% CI 0.465–0.819; p = 0.0009), and PFS (HR: 0.547; 95% CI 0.415–0.721; p < 0.0001), while RT + TMZ showed a trend toward improved OS (HR: 0.913; 95% CI 0.666–1.252; p = 0.421) and PFS (HR: 1.270; 95% CI 0.870–1.855; p = 0.215), without statistical significance.

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