TAMs-mediated resistance to oncolytic virus M1 in solid tumors.

J Immunother Cancer · 2025 · PMC12625921 · PMID 41238218

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did not reach statistical significanceno p-value reported

Correlation analysis revealed a strong positive correlation between OVM treatment resistance and M1-like TAMs infiltration (R2=0.9345), while the correlation with M2-like TAMs did not reach statistical significance (R2=0.7782), though it still suggests a potential role in the resistance mechanism ( figure 1F,G and online supplemental figure S1B,C ).

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