A single-cell transcriptomic atlas elucidates the hair cycle and apoptosis mechanisms in goat hair follicles.

Some specific genes involved in cell differentiation and translation, such as KRT19, LOC102171034, and LOC108634081, are mainly enriched in Catagen ( Figure 4C ).On Telogen, LOC108636537 and LOC102174421 showed a trend of increasing first and then decreasing along the pseudotime axis and promote the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; API5 showed the opposite trend along the pseudotime axis ( Figure 4C ), API5 is known to be highly expressed in the Anagen period, but the expression level is reduced in the Catagen and Telogen ( Figure 4D ).

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