Effect of low bicarbonate substitution solution on CO<sub>2</sub> removal rate in the combined system of extracorporeal CO<sub>2</sub> removal and continuous renal replacement therapy.

In contrast, compared with 25 mmol/L, a low bicarbonate concentration of 16 mmol/L in the substitution solution significantly increased CO2 elimination, although the difference in patients did not reach statistical significance, which is likely due to the variation in blood flow.

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