Gli1-expressing stromal cells are highly reparative precursors of long-lived chondroprogenitors in the fetal murine limb.

Nat Commun · 2025 · PMC12627582 · PMID 41253754

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This result demonstrated that Gli1-derived chondrocytes are required to compensate for cell-cycle arrest in the fetal cartilage, although it did not rule out more subtle effects in Gli-Cart-DTA pups, which showed a trend towards decreased bone length.

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