Genetic heterogeneity and homogeneity among orofacial cleft subtypes: genome-wide association studies in the cleft collective.

Hum Mol Genet · 2025 · PMC12627943 · PMID 41075272

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hedged sentence

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closest p · 1.0× alpha

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boldest claim

The sentences

nominally significantP < 0.05actually significant

Lead SNPs rs4112328 ( LHX8, 1p31.1 ) , rs28361060 ( TSBP1, 6p21.32) and rs7870795 (FOXE1, 9q22.33) had the smallest p-values in the "all cases" GWAS and were nominally significant ( P < 0.05) in the same direction across all subgroups.

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