Integrated bulk and single-cell transcriptomic profiling reveals NECTIN-TIGIT interaction underlies T cell exhaustion in papillary thyroid carcinoma.

Clin Exp Med · 2025 · PMC12628383 · PMID 41249602

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did not reach statistical significanceno p-value reported

The phase III SKYSCRAPER-01 trial in PD-L1-high NSCLC failed to meet its primary endpoints of overall survival and progression-free survival, while the SKYSCRAPER-02 trial in extensive-stage small cell lung cancer also did not reach statistical significance for its primary endpoints [ 66 ].

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