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Spike conformational and glycan heterogeneity associated with furin cleavage causes incomplete neutralization of SARS-CoV-2.

Nat Commun · 2025 · PMC12630640 · PMID 41257850

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showed a trendno p-value reported
The data showed a trend that subsequent variants are more resistant to sera induced by earlier variants not only in terms of potency but also the efficacy of neutralization.

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