The efficacy and safety of low-intensity focused ultrasound pulses for prolonged disorders of consciousness: a study protocol for a randomized controlled trial.

Front Neurol · 2025 · PMC12631113 · PMID 41281547

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did not reach statistical significanceno p-value reported

Third, for transcutaneous auricular vagus nerve stimulation (taVNS), a 2023 randomized double-blind controlled trial ( 17 ) involving 57 DoC patients found that while the intervention group showed higher CRS-R scores post-treatment compared to the control group, the difference did not reach statistical significance.

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