Interleukin-6 levels and their haplotypes are associated with serological autoantibodies status and clinical activity in rheumatoid arthritis.

Front Immunol · 2025 · PMC12631633 · PMID 41280923

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However, the GG haplotype (rs1800797/rs1818879) was associated with the susceptibility to RA (OR = 1.34, 95% CI, 1.01–1.79, p = 0.03), while the GGG haplotype showed a trend toward RA susceptibility without reaching significance (OR = 1.34, 95% CI, 0.99–1.80, p = 0.05) ( Table 3 ).

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