Barely Significant
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Prognostic value of kappa free light chain index in patients with primary progressive multiple sclerosis.

Front Immunol · 2025 · PMC12634365 · PMID 41280940

Europe PMCDOI
1
hedged sentence
0.3280
closest p · 6.6× alpha
0.3280
boldest claim

The sentences

did not reach statistical significancep = 0.328not close (p > 0.1)
The median κ-FLC index determined at baseline was numerically higher in progressive patients (43.7; 15.5–108.2) compared to the stable group (26.1; 13.9–75.8); however, this difference did not reach statistical significance (p = 0.328; Table 2 ). κ-FLC index does not predict disability progression in PPMS Multivariable Cox regression analysis showed that the κ-FLC index was not a statistically significant predictor of time to disability progression [hazard ratio (HR) 1.0, p = 0.950].

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