Impact of metagenomic sequencing on clinical outcomes in patients with suspected central nervous system infections: a retrospective case-control study.

Front Cell Infect Microbiol · 2025 · PMC12634551 · PMID 41278475

Europe PMC DOI

hedged sentences

0.0890

closest p · 1.8× alpha

0.0890

boldest claim

The sentences

a mild trendp=0.089so close (0.05 < p ≤ 0.1)

17.2%), and a mild trend toward interaction was observed (p=0.089) ( Figure 4A ).

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did not reach statistical significanceno p-value reported

Although the clinical improvement rates between the mNGS and CMT groups did not reach statistical significance in the sepsis subgroup analysis, the limited sample size precludes definitive conclusions regarding the influence of sepsis.

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