R-Spondin1 Regulates Fate of Enteric Neural Progenitors via Differential LGR4/5/6 Expression in Mice and Humans.

Cell Mol Gastroenterol Hepatol · 2026 · PMC12634853 · PMID 40998011

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did not reach statistical significanceno p-value reported

It is noteworthy that, although the pro-proliferative effect of RSPO1 on P75-expressing neural cells was readily detectable and statistically significant using the proliferation marker Ki67, the increase in the total P75-positive population compared with all DAPI-positive cells was modest and did not reach statistical significance.

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