High-resolution proteomics unveils salivary gland disruption and saliva-hemolymph protein exchange in Plasmodium-infected mosquitoes.

Nat Commun · 2025 · PMC12635079 · PMID 41266344

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a notable trendno p-value reported

Analysis of the differentially enriched or depleted proteins revealed a notable trend: several hemolymph proteins that were enriched in the SGs following sporozoite invasion exhibited depletion in the saliva collected from infected mosquitoes (Figs. 2 d, 7c, d , and Supplementary Data 7 , 12 , 13 ).

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a strong trendno p-value reported

Interestingly, a strong trend of protein depletion was observed, with no proteins enriched in saliva from iSGs.

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