Comparing early surgical outcomes between total neoadjuvant therapy and standard long course chemoradiotherapy for rectal cancer.

World J Gastrointest Oncol · 2025 · PMC12635705 · PMID 41281487

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did not reach statistical significanceno p-value reported

Surgical specimen quality was consistently high regardless of neoadjuvant protocol: R0 resection was achieved in 93.1% of TNT-RAPIDO cases and 90% of LCCRT cases, while complete TME was recorded in 100% and 94.3%, respectively, differences that did not reach statistical significance.

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