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Response to the Letter to the Editor "Opinion on nerve-sparing radical hysterectomy".

J Gynecol Oncol · 2025 · PMC12636097 · PMID 41253399

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a clear trendno p-value reported
As stated in our manuscript, “all radical hysterectomies in this study were supervised by an attending physician.” As demonstrated by the SHAPE trial and JCOG1101, there is a clear trend toward surgical de-escalation, and the number of candidates for radical hysterectomy has significantly decreased [ 2 , 3 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.