Immunogenicity and efficacy of homologous and heterologous NDV and MVA SARS-CoV-2 vaccines in mice and hamsters.

NPJ Vaccines · 2025 · PMC12638851 · PMID 41271759

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Moreover, in hamsters, intranasal vaccination with NDV-HXP-S conferred protection of the upper respiratory tract, and the NDV-HXP-S/MVA-S(3P) regimen showed a trend toward reduced direct contact transmission of SARS-CoV-2, although the limited sample size precludes definitive conclusions.

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