A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo release.

Nat Commun · 2025 · PMC12639036 · PMID 41271724

Europe PMC DOI

hedged sentence

0.0860

closest p · 1.7× alpha

0.0860

boldest claim

The sentences

showed a trendp = 0.086so close (0.05 < p ≤ 0.1)

Plasmid DNA transfection of the same constructs showed a trend towards a low level of toxicity ( p = 0.086), and treatment with Triton X-100 resulted in complete loss of viability.

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