Barely Significant
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HIV-1 envelope trimer vaccine induces sex-associated differences in antibody responses: a phase 1 clinical trial.

Nat Commun · 2025 · PMC12639139 · PMID 41271616

1
hedged sentence
0.0040
closest p · 0.1× alpha
0.0040
boldest claim

The sentences

did not reach statistical significancep < 0.004actually significant
We did observe inverse correlations within the female and male groups between testosterone and IgG3 levels, and oestradiol and IgG3 levels, but these correlations did not reach statistical significance after Bonferroni multiplicity correction (threshold p < 0.004) (Supplementary Fig. 8a–g ).

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