Unsaturated alginate oligosaccharides alleviate insulin resistance and fatty liver in non-obese NAFLD mice by regulating bile acid metabolism through gut microbiota.

Metabol Open · 2025 · PMC12639454 · PMID 41280282

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an increasing trendno p-value reported

Additionally, the relative abundances of Patescibacteria , Actinobacteriota , and Verrucomicrobiota showed an increasing trend ( Fig. 4 A).

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did not reach statistical significanceno p-value reported

Although some indicators did not reach statistical significance, these results suggest that both UAOS and alginate help to improve liver function and reduce inflammation in non-obese NAFLD mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.