MAFLD in Egyptian non-dialysis CKD Patients: Frequency, fibrosis severity, and risk factors.

PLoS One · 2025 · PMC12643317 · PMID 41284717

Europe PMC DOI

hedged sentences

0.3940

closest p · 7.9× alpha

0.3940

boldest claim

The sentences

did not reach statistical significancep = 0.394not close (p > 0.1)

While fibrosis grade distribution did not reach statistical significance (p = 0.394), clinically relevant patterns emerged: late-stage CKD patients had a 38% higher prevalence of moderate fibrosis (F2: 68.8% vs 50%) and nearly double the proportion of advanced fibrosis (F3-F4: 14.6% vs 25%).

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borderline significantno p-value reported

HOMA-IR became borderline significant, implying insulin resistance’s impact is largely treatable with current therapies.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.