Barely Significant
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Causal associations of inflammatory proteins and plasma metabolites with Clostridium difficile colitis: A Mendelian randomization study.

Medicine (Baltimore) · 2025 · PMC12643595 · PMID 41305795

Europe PMCDOI
1
hedged sentence
0.0310
closest p · 0.6× alpha
0.0310
boldest claim

The sentences

only marginally significantP = .031actually significant
Specifically, the mediation analysis revealed a possible pathway that IL-2RB exerts its causal effect on CDC through spermidine-to-choline ratio, though the causal effect of IL-2RB on spermidine-to-choline ratio was only marginally significant ( P = .031), which needs to be further validated in larger cohorts.

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