Inflammation and oxidative stress are associated with major adverse cardiovascular events in adults with preclinical hypertension.

In addition, utilizing the Jonckheere-Terpstra test, we found that all the biomarkers had a positive trend with increasing BP categories.

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Of note, interleukin-6 improved model fit, as reflected by a lower AIC; however, its association with MACE did not reach statistical significance.

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