Maternal monosaccharide diets modulate melanocortin-4 receptor signaling and metabolic state in rat offspring.

Pharmacol Rep · 2025 · PMC12647268 · PMID 40956393

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MANOVA at PND63 revealed significant multivariate effects of diet (Wilks’ λ = 0.36, F 4, 82 = 13.61, p < 0.0001) and sex (Wilks’ λ = 0.36, F 2, 41 = 35.97, p < 0.0001), whereas the diet × sex interaction was not statistically significant (Wilks’ λ = 0.82, F 4, 82 = 2.14, p = 0.08), though it approached significance.

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