Weight gain under antipsychotic and mood stabilizing treatment: a narrative review about mechanisms and future options.

Nevertheless, a more recent systematic review and meta-analysis evaluating weight change between lithium treated patients compared to baseline did not reach statistical significance (weight gain of 0.462 kg in the lithium group) (Gomes-da-Costa et al. 2022 ); still weight gain seemed to be significantly greater in interventions of 12 weeks or less (Gomes-da-Costa et al. 2022 ).

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