Effects of Metformin on children with Fragile X Syndrome: a randomized, double-blind, placebo-controlled trial.

Mol Autism · 2025 · PMC12648774 · PMID 41291951

Europe PMC DOI

hedged sentence

0.0950

closest p · 1.9× alpha

0.0950

boldest claim

The sentences

did not reach statistical significancep = 0.095so close (0.05 < p ≤ 0.1)

The total ABC score reduction was more pronounced in the metformin group (-16.60 ± 15.31) compared to the placebo group (-4.00 ± 23.67), though this difference did not reach statistical significance ( p = 0.095).

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