As for apoptosis genes, the expression of P53 ( Figure 4 A) in the treated group showed an overall trend of increasing and then decreasing, and the peak value of the high-concentration group (6 h) was delayed compared with that of the medium and low-concentration groups (3 h); and it was 7.4 times higher than that of the control group.
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Xingkai Lake Topmouth Culter (<i>Culter alburnus</i>) Exhibits Biochemical and Histopathological Alterations upon Acute Ammonia Exposure.
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In terms of liver function indexes, both AST ( Figure 2 A) and ALT ( Figure 2 B) activities showed an increasing trend and were positively correlated with the exposure concentration.
in the low-concentration group was higher than that of the control group ( p < 0.05), while both the medium and high-concentration groups were significantly higher than the control group ( p < 0.05) throughout the exposure period and showed some degree of fluctuation; the MDA content ( Figure 2 F) showed a trend of increasing and then decreasing in all treatment groups, with the low-concentration group reaching a peak at 3 h and being significantly higher than the control group ( p < 0.05), and the medium-concentration group reaching a peak at 6 h and being significantly higher than the control group ( p < 0.05), the high-concentration group peaked at 12 h, and its MDA content from 6 to 48 h was significantly higher than that of the control group ( p < 0.05). 3.3.