Preclinical Mechanistic Evaluation of Hyaluronan/Niacinamide (Vitamin B3) Hydrogels: Toward an Enhanced Viscosupplement System with Ancillary Anti-Arthritic Attributes.

Bioengineering (Basel) · 2025 · PMC12649763 · PMID 41301202

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

showed a trendno p-value reported

However, in Raw 264.7 macrophages, B3 and the HA/B3 combination showed a trend towards toxicity at higher concentrations, although the differences compared to untreated cells were not statistically significant ( Figure 1 B,C).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.