Barely Significant
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Integrating 3D Osteocyte Culture, Microgravity Simulation, and Fluid Flow Reveals Mechanisms of Osteocyte Mechanosensation and Calcium Signaling Altered by Disuse.

Biomolecules · 2025 · PMC12649886 · PMID 41301453

2
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0.0776
closest p · 1.6× alpha
0.0776
boldest claim

The sentences

a mild trendp = 0.0776so close (0.05 < p ≤ 0.1)
However, we did note a mild trend for PMD formation to be associated with a longer calcium wave duration ( p = 0.0776; Figure 4 C) as compared to non-wounded cells.

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Interestingly, although we observed a microgravity-related increase in the average duration of the highest calcium wave in earlier experiments ( Figure 3 F), this trend did not reach statistical significance in the follow-up experiments with the FITC-dextran PMD tracer where a smaller number of ROIs were considered ( Figure 4 C).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.