Comparative Efficacy of Platelet-Rich Fibrin, Freeze-Dried Bone Allograft, or Spontaneous Healing for Alveolar Ridge Preservation: Systematic Review and Meta-Analysis.

Bioengineering (Basel) · 2025 · PMC12650340 · PMID 41301209

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a favorable trendno p-value reported

Although PRF had a favorable trend compared to FDBA, it was not statistically significant due to high heterogeneity, while FDBA did not show a consistent benefit over blood clot. 3.6.

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did not reach statistical significanceno p-value reported

While PRF also showed a favorable trend over FDBA in histometric bone formation, the result did not reach statistical significance due to high heterogeneity ( Figure 6 ).

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