Exosomal Protein Markers as Potential Non-Invasive Biomarkers for Colorectal Cancer.

In participants aged 60 and older, the difference did not reach statistical significance ( p > 0.05), although a trend toward higher HSP70 levels in men was noted, which may be explained by the decline of androgens with age influencing stress protein expression in tumor and stromal cells and thereby shaping the exosomal cargo [ 49 ].

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